LuminoDx Inc

AVITI24 Multiomics

 

Empowering Precision Medicine with AVITI24™ and Teton™ Technology

As an Element Biosciences Certified Service Provider, we integrate AVITI24™ system into our workflow and provide researchers with unparalleled access to 5D Multiomics – simultaneously capturing RNA, proteins, phospho-proteins, and cell morphology at subcellular resolution, all from a single sample.

Our Core AVITI24™ Services

We specialize in high-dimensional spatial analysis that bridges the gap between traditional sequencing and functional cell biology.

1. Teton™ CytoProfiling & Spatial Transcriptomics

Gain a holistic view of biological systems. Our Teton™ services allow for the spatial co-detection of multiple analytes without the need for complex library preparation.

  • Spatial Transcriptomics: Profile up to 350 RNA targets with subcellular spatial context.
  • Protein & Phospho-Protein Mapping: Detect up to 128 proteins, including critical signaling and surface markers.
  • Subcellular Resolution: Visualize 6 key morphological features (Nucleus, Membrane, Actin, etc.) to link molecular data to cell structure.

Applications: Ideal for Oncology (MAPK signaling, T-cell exhaustion), Immunology, and Neuroscience research.

2. Direct In-Sample Sequencing (DISS)

Skip the library prep and sequence directly within the cell. Our Direct-In-Sample Sequencing (DISS) workflow is a game-changer for:

  • In Situ RNA Sequencing: Targeted or untargeted 3’ transcriptomics (up to 100bp).
  • CRISPR Screening: Direct guide RNA (gRNA) sequencing combined with proteomic and morphological readouts.
  • Rapid Turnaround: Move from sample to actionable insights in as little as 24 hours.

3. High-Accuracy DNA Sequencing

While our focus is on spatial multiomics, we continue to offer best-in-class DNA sequencing services powered by Avidity™ Chemistry.

  • Q50+ Accuracy: Industry-leading data quality for rare variant detection and MRD research.
  • Flexible Throughput: Independent dual flow cells allow us to scale from small targeted panels to whole-genome sequencing (WGS) efficiently.

Why Partner with LuminoDx?

  • Certified Excellence: As a Certified Service Provider, our laboratory has undergone independent validation by Element Biosciences and others to ensure the highest standards of data quality and performance.
  • Expert Insight: We combine 35 years of CRO experience with cutting-edge technology like Thermofisher’s Olink platform, Biotechne’s ELLA system and the ELEMENT AVITI24™ Omic’s platform to support drug development, biomarker discovery, and clinical research.
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